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教学日历

作者: 时间:2009-09-20 点击数:

(2009-2010 Autumn term)Pharmacology teaching schedule for foreign students

classroom: 2205                                      Dean (signature):

object

2007 degree

number

84

time

2009.8 -2010.1

week

order

hours

date

section

contents

requisition

 responsible teachers and academic title

3

1

2

8.25

1、2

UNIT I Introduction to Pharmacology

·         Understanding the concepts such as pharmacology, drug and the contents of pharmacology study.

·         Knowing of pharmacological developing history.

 

Lecturer

Jin yingli

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

2

2

8.28

1、2

Chapter2: Pharmacokinetics and Drug Receptors

·         Mastering the therapeutical effect and adverse reaction of drugs.

·         Mastering the relationship between drug dosage and effect.

·         Mastering the concepts: potency,ED50,LD50 and therapeutic index, agonist and antagonist.

·         Understanding the effects and actions of drugs.

·         Understanding the mechanisms of drugs action and structure-activity relationships.

·         Understanding the interaction between drug and receptor.

·         Knowing of transmembrane signaling and infra-cell message.

 

4

3

2

8.31

3,4

Chapter 3: Absorption, Distribution, and Elimination of Drugs

·         Mastering the in vivo procedure of drugs -ADME system.

·         Mastering the concepts including first-pass elimination ,hepatic microsomal mixed function oxidase system, bioavailability, clearance, apparent volume of distribution, compartment model and half-life.

·         Mastering the precluding traits of the first-order kinetics and zero-order

4

2

9.4

5,6

 

·          kinetics.

·         Understanding the traits of active transport and passive transport.

·         Understanding the concentration-time relationship and concentration-time curve.

·         Understanding concentration-time curve of continuous administration and homeostasis blood-drug concentration.

·         Lecture: Understanding the main pharmacokinetic parametes and significance.

 

5

5

2

9.7

5,6

 

 

 

 

Chapter4 The factors affect metabolism

·         Mastering the concepts including placebo, tolerance, resistance, habituation, addiction and dependence.

·         Mastering the concepts including threshold dose, minimal effective concentration, minimal toxic amount and maximal effect.

·         Knowing of the factors affecting drugs effects.

 

6

2

9.10

5,6

chapter 5 The drugs Affecting the Autonomic Nervous System

chapter 6 Cholinergic Agonists

·         Knowing of the efferent neurotransmitter and receptor.

·         Knowing of the basic action and classification of drugs acting on the efferent nerve system.

Associated Pro.

Qiao ping

 

6

7

2

9.14

1, 2

 

·         Mastering the pharmacological action and clinical application of pilocarpine acting on eyes

·         Mastering the pharmacological action and clinical application of neostigmine belonging to easy-changing anti-cholinesterase drugs.

8

2

9.17

5,6

chapter7  Cholinergic Antagonists

·         Mastering the pharmacological action , clinical application,  adverse reaction and intoxication of atropine.

·         Knowing of the classification of cholinoceptor blocking drugs.

·         Knowing of the main traits of N receptor blocking drugs.

·          

7

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

8

 

9

2

9.21

5,6

chapter8 Adrenergic Agonists

·         Mastering the pharmacological action and clinical application of the drugs including noradrenaline, hydroxynorephedrine, adrenaline, dopamine, ephedrine, isoprenaline, and dobutamine.

·         Knowing of the chemical structure and structure activity relationship of adrenoceptor agonists.

 

10

2

9.24

5,6

chapter9 Adrenoceptor blocking drugs

 

·         Mastering the pharmacological action and clinical application of phentolamine belonging to α receptor blocking drugs.

·         Mastering the classification, pharmacological action ,clinical application ,adverse reaction and contraindication of βreceptor blocking drugs.

·         Knowing of the classification of adrenoceptor blocking drugs and the  representative drugs.

 

11

2

9.28

5,6

chapter17 Sedative-hypnotics

 

·         Mastering the pharmacological action and clinical application of benzodiazepines.

·         Understanding the traits of barbiturates.

 

Associated Pro.

Ji Yingshi

 

9

12

2

 

10.9

1、2

chapter18,19 Antiepileptic drugs and Antispasmodic drugs

 

 

 

 

 

·         Mastering the pharmacological action and clinical application of the drugs: sodium phenytoin, carbamazepine, Phenobarbital, primidone, ethosuximide, sodium valproate and magnesium sulfate.

·         Understanding the adverse reaction of the anti-epileptic drugs and antispasmodic drugs commonly used.

·         Knowing of the trait of action of other anti-epileptic drugs.

10

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

13

2

10.12

3,4

Drugs acting on Parkinson's disease and affecting Alzheimer's disease

 

·         Mastering the pharmacological action and clinical application of the drugs : levodopa, carbidopa and trihexyphenidyl.

·         Understanding the traits of action of other drugs acting on Parkinson's disease.

·         Knowing of the principle of episode and the classification of drugs acting on Parkinson's disease.

·         4.Knowing of the drugs affecting Alzheimer's disease.

 

 

14

2

10.15

1、2

chapter 20 Drugs acting on the psychiatric disorder

 

·         Mastering the pharmacological action, clinical application  and adverse reaction of chlorpromazine.

·         Mastering the pharmacological action and adverse reaction of Lithium Carbonate.

·         Mastering the pharmacological action and clinical application of imipramine.

 

 

 

 

 

11

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

15

2

10.19

3,4

chapter 21 Analgesics

 

·         Mastering the pharmacological action, clinical application and adverse reaction of morphia belonging to opium Alkaloids.

·         Understanding the traits of man-made synthesis opium analgesics such as pethidine

·         Understanding the mechanisms of pharmacological action of analgesics.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

16

2

10.23

7,8

chapter 22 Anti-inflammatory drugs

 

·         Mastering the pharmacological action, clinical application and adverse reaction of aspirin and acetaminophen.

·         Mastering the pharmacological action, clinical application and adverse reaction of other anti-inflammatory drugs. 

·         Understanding the pharmacological action and clinical application of ibuprofen.

·         Understanding the identical traits of anti-inflammatory drugs. 

·         Knowing of the traits of action of selective COX-2 inhibitor

12

 

17

2

10.27

3,4

chapter 24 Drugs acting cardiovascular system

 

·         Mastering the pharmacological action, traits of action and clinical application of calcium channel blockers.

·         Understanding the concepts and classification of calcium channel blockers.

·         Knowing of the traits of drugs acting on k+ and Na+ channel.

 

Associated Pro.

WeiZhengren

 

 

 

18

2

10.29

7,8

chapter25 Anti-arrhythmic Drugs

 

·         Mastering the classification of anti-arrhythmic drugs.

·         Mastering the pharmacological action, clinical application and adverse reaction of quinidine.

·         Mastering the pharmacological action, clinical application and adverse reaction of the drugs: lidocaine, phenytoin sodium, propranolol, amiodarone and verapamil.

 

 

 

 

 

 

 

 

 

 

19

2

10.30

7,8

·         Understanding the electrophysiological background of anti-arrhythmic drugs.

·         Knowing of the therapeutic principle of swift arrhythmia and the reasonable application of drugs.

13

20

2

11.2

3、4

chapter 27 Drugs treatment of heart failure

 

·         Mastering the pharmacological action, clinical application and adverse reaction of digoxin.

·         Mastering the pharmacological action, mechanism, clinical application and adverse reaction of ACE inhibitor.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

14

 

 

 

21

2

11.6

7,8

 

·         Mastering the mechanism of action of βadrenoceptor blocker effecting on the treatment of CHF.

·         Knowing of the pathophysiology of CHF and the link of action of drugs.

·         Knowing of the application of diuresis drugs used in the treatment of CHF.

·         Knowing of the main traits of positive intropic drugs belonging to non- cardenolide.

 

22

2

11.10

3、4

chapter 28 Drugs used for the treatment of angina

 

·         Mastering the mechanisms of pharmacological action, clinical application and adverse reaction of the drugs: nitroglycerin, βadrenoceptor blocker and calcium channel blockers used for the treatment of myocardial ischemia.

·         Knowing of the equilibrium relationship between the attack of angina pectoris and the supplying and consuming oxygen of myocardium.

 

23

 

 

 

 

 

 

 

 

 

2

11.11

7,8

Chapter30 Anti-hypertensive drugs

 

·         Mastering the mechanism of action and clinical application of loop diuretics.

·         Mastering the anti-hypertensive action, mechanism, and adverse reaction ofβ-adrenergic antagonists.

24

2

11.13

5,6

 

·         Mastering the anti-hypertensive action of the drugs: calcium channel blockers, angiotensin converting enzyme inhibitors, sympathetic inhibitors, AngII receptor antagonists, such as losartan and hemangiectasia drugs.

·         Understanding the classification of anti-hypertensive drugs.

·         Understanding the anti-hypertensive drugs in combination.

 

15

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

16

 

25

2

11.16

1,2

chapter 26 Diuretics and Dehydrat agents

 

·         Mastering the site and mechanisms of action of diuretics.

·         Mastering the pharmacological action, clinical application and adverse reaction of furosemide belonging to high potency diuresis

·         Mastering the pharmacological action, clinical application and adverse reaction of thiazides belonging to middle potency diuresis .

·         Knowing of the mechanisms of action, clinical application and adverse reaction of low potency diuresis .

·         Knowing of the pharmacological action, clinical application and adverse reaction.

 

Lecturer

Guan fengying

 

26

2

11.23

3,4

chapter 31 Drugs acting on the blood and the blood –forming organs

 

·         Mastering the pharmacological action, clinical application, adverse reaction and intoxication prevention of  heparin and coumarin.

·         Mastering the classification of anti-platelet drugs and the pharmacological action, clinical application, adverse reaction of its representive drug:aspirin

·         Mastering the pharmacological action, clinical application of streptokinase belonging to fibrinolysis drugs.`

·         Mastering the clinical application and adverse reaction of vitamine K belonging to promoting blood coagulative drugs 

·         Mastering the pharmacological action, clinical application of anti-anemia drugs: iron agents, folic acid and vitamin 12.

·         Mastering the pharmacological action and clinical application of dextran.

 

27

2

11.25

7,8

chapter 32 Antitussives, Expectorants and Antiasthmatic drugs

 

·         Mastering the mechanism of action of every variety of anti-asthmatic drugs.

·         Mastering the pharmacological action, clinical application of the drugs: albuterol, terbutaline, theophylline and cromolyn sodium.

·         Knowing of the clinical applications of antitussives and antitussives.

17

28

2

11.30

3,4

chapter 11 Adrenal Cortical Hormones

 

·         Mastering the pharmacological action, clinical application, adverse reaction and contraindication of adrenal cortical hormones.

·         2   Understanding the course and usage of glucocrticoids.

·         Knowing of the structure-activity relationship of glucocorticoids.

 

29

2

12.2

7,8

chapter 12 Thyroid and Antithyroid drugs

 

·         Mastering the pharmacological action ,clinical application and adverse reaction the drugs:thioureas, iodine and iodide.

·         Understanding the pharmacological action and clinical application of thyroid hormone.

·         Knowing of the synthesis, excretion and accommodation of thyroid hormone.

18

 

 

 

 

 

 

 

 

 

 

 

 

30

2

12.7

1、2

chapter 13 Insulin and Oral hypoglycemic drugs

 

·         Mastering the clinical application and adverse reaction of insulin preparation.

·         Mastering the pharmacological action ,clinical application and adverse reaction of sulfonylureas and biguanides.

 

19

31

2

12.14

3,4

Chapter 35

Antimicrobial Drug Outline

Chapter 36

β-Lactam Antibiotics

 

·         The brief developing history of anti-microbial drugs.

·         Nouns and terms.

·         The mechanism of action of anti-microbial drugs.

·         The tolerance of microorganism.

·         the anti-microbial spectrum, mechanism of action, in vivo procedure and clinical application of benzylpenicillin.

·         the traits of demi-synthesis penicillin; Mastering the antibacterial action and  clinical application of Ampicillin and Amoxicillin.

 

Professor Chen Li

 

 

 

 

 

 

 

 

 

 

 

 

32

2

12.18

5,6

Chapter 36

 (continue)

Chapter 37 Macrolide, Erythromycin

·         To know cephalosporin classification and varied representative drugs on antibiotics

·         To know the erythromycin application and actions

·         To know the features of Roxithromycin and Azithromycin

20

33

2

12.21

3,4

 

Chapter 38 Aminoglycosides and poly

 

 

·          the action, mechanism, clinical application and adverse reaction of aminoglycosides.

·         the clinical application of aminoglycosides frequently used such as gentamicin, tobramycin and amikacin.

·         Knowing of the traits of action of colistin.

 

 

34

2

12.23

7,8

Chapter 39 Tetracyclines and Chloramphenicol

Chapter 40 Man-made synthesis Antibacterial drugs

 

·          the antibiotic action, clinical application and adverse reaction of chloramphenicol.

·          the antibiotic mechanism, clinical applications and adverse reaction of quinolone

·          the antibacterial action and mechanism of sulfonamides.

·          the traits of action of SD and SMZ and the evidence and significance of TMP and sulfonamides in combination.

21

35

2

12.31

3,4

Chapter 42 Anti-tuberculosis drugs and antileprosy drugs

 

 

·         1.the traits, clinical application and  adverse reaction of the first-selected anti-tuberculosis drugs such as isoniazid, rifampicin and ethamnbutol.

·         the main traits of the second-selected anti-tuberculosis drugs.

·         the applicative principle of anti-tuberculosis drugs.

·          the main traits of the anti-leprosy drugs.

22

36

2

1.7

5,6

 

Chapter 43 The available application of antibiotics

Chapter 45 Anti tumor drugs

 

·         The reasonable application of antibiotics

·         The classification of anti tumor drugs

·         To know the features of varied anti tumor drugs

 

 

 

 

 

 

 

                   

 

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