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ѪСۼ C. VSMC ֳǨƣ D. c-fosHMG-CoA ԭøECM ıԼECM (fibronectin, laminin, ԭ) ĺϳɣ E. LDL ת¼IL-6IJڡ͵̴ ڷڣ ѪܲƼʱ ԴҶ߲ءѹ ԴǰҶACTHTSHټ ȵءȩͪ ƽͷNACa2+׿ҩ÷ʽPowerPoint ʾĸAdverse reactionsContraindications Clinical uses Ѫϵͳ Ѫѹ ĿѪѹ Ľʹ (angina pectoris) ͣϢʱѡҩ ȶͣۡʱѡάסض׿ ȶͣҹɷأά׺͵׿Ч ʧѡ verapamil ͷˡ ĹܲȫЧ׿,ѡ amlodipine ʺļ:Dҷʺleft ventricular hypertrophy, LVH LVHΪѪܷʺͲߵҪΣ LVHغ ҳӯ ʧķʼس̶ӣ ҹܳڽԽͣ˥ ׿˳ӦԡԤʧʹʺļС ѪܼnimodipineflunarizineѪܾμѪͷʹ ŵnimodipinenifedipine ֧ʳʧڻ֢θԸʹʹȡverapamil3 ø׿ҩnifedipine-ƷʹClinical uses AmlodipineNimodipine-Īͨ) Verapamil-첫(isoptin) Diltiazem Other drugshQuestions 1. ׿ҩҩüٴӦá 2. verapamilnifedipine  D<,{2 Actions and clinical uses pharmacological actions [_v\O(u [@{v\O(u [vQ[s^nv\O(u 9eU~~@Am vQ[\O(u [}%%%%f%#0!#  ,2$ F>& [_v\O(u< &$f$fF'`R\O(u '`sT'` O[\O(u Ob:@_\O(u b_S\O(u$$f3$$# % '`R\O(u negative inotropic action " tQKY-6e)1vPT _6e)'`Q1_ " _'lQ\ " ]x0Ws^hs:N{_vck'`R\O(u " ~b^s|T0W\kxSS'`R\O(u:_Lj f$ $$$$$$$$$D   8  G?H% '`sT'` O[\O(u negative chronotropic and conductive actions " z?b~T?b[~I{baS^~ހv0vdgT4vbadg/fCa2+QAm@b_w " Calcium anatagonists  MNOz?b~ꁋ_'` _sQba; ?b[~ O[^Qba; ^ gHe N^g mdbԏoR.x f(f (,("0$          '($$* l  ) H@IA% Ob:@_\O(u>  f(f $ _:@:'lހQCa2+o;mxv0ˆ}vv0ATPvI{~g4xOW_~ހNTOW{k_~gTR4xOW Ca2+bboOb:g6R ;eCa2+QAm _6e)RMNO 'lϑQ\ ib _Q XR_@'lO~ b'lS\O(u $9x x, " f3x              % f3r  %JB% b_S\O(u* (f$b6RCa2+QAm~ހQCa2+ f>fl_ S \O(u:gt  _R MNOTw Q\gN͑vQn'`uVP[vʑ>eT/bbb[NvOu\O(u(TNF -TIL)Y@{'} _ }II0Qv }-10?Q6ZI{#nJn     $$.   r: KC& [@{v\O(u< &$f&$(;N _R [Y q_T\N, NXRY [ϑ Q  _'Yv@{T\v;R@{ OQ AmϑSOg_sϑXR @{XR@Amϑ<\0Ws^0lBhU YhT@{ducu xEx$$$$        \LD& [vQ[s^nv\O(u< &$f$ (  ~g_/el{s^n2lTUSQ\~ ʑ>eTLTD4vTb Q\|mvRl 'YBRϑe~g_mSS0ƀS0?\{ SP[[s^nu\O(u Np{|v\O(u g:_}}}#} $$ $$ ,BME& 9eU~~@Amv\O(u> $f$   b6R@\gZƖ Ca2+QAm[@\gZ Ɩw͑\O(u XR~~ހSb_R MNO@m|n '`~~ހQCa2+XY vQSb_R NM $$$ $ $$ $$  F / NF& vQ[\O(u % bR |7hlxS A. 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